Red blood cell alloantibodies and autoantibodies: different presentation, same physiopathology
نویسندگان
چکیده
منابع مشابه
Red cell alloantibodies in Lao blood donors.
Data of the prevalence of red cell alloantibodies in blood donors will assist in improving safe blood supply for patients needing transfusion. The purpose of this study was to determine prevalence of red cell alloantibodies in Lao blood donors. Antibody screening and identification by multiple phase indirect antiglobulin standard tube assay were performed in serum samples from 1,181 blood donor...
متن کاملEffect of superposition and masking between red blood cell autoantibodies and alloantibodies.
This study aimed to explore the law of superposition and masking between autoantibodies and alloantibodies, and to ensure the detection of alloantibodies and to improve the safety of warm autoimmune hemolytic anemia patients. Eight kinds of commercial IgG red blood cell antibody reagents were serially diluted, and 3 kinds of antibodies at dilutions showing a continuous gradual decline in agglut...
متن کاملPrevalence of Alloantibodies and Autoantibodies in Transfusion Dependent Thalassemia Patients
Background: The development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. Also, Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. We studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in Ilam province...
متن کاملClinical relevance of silent red blood cell autoantibodies.
The diagnosis of autoimmune hemolytic anemia (AIHA) is based on the evidence of anemia, hemolysis and the detection of red blood cell (RBCs) autoantibodies. The absence of detectable RBC autoantibodies does not always exclude autoimmune hemolysis. Conversely, the presence of RBC autoantibodies is not always associated with hemolytic anemia. Silent RBC autoantibodies have been detected in health...
متن کاملA comparison of two automated methods for the detection and identification of red blood cell alloantibodies.
BACKGROUND The aim of this study was to compare the routine use of two automated systems (OrthoAutoVue Innova, microcolumn, and Immucor Galileo, solid phase) for the screening and identification of irregular red blood cell alloantibodies in samples, analysed in our Transfusion Service during 6 months of normal activity. The study focused particularly on an evaluation of the repeatability of the...
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ژورنال
عنوان ژورنال: Hematology, Transfusion and Cell Therapy
سال: 2018
ISSN: 2531-1379
DOI: 10.1016/j.htct.2017.09.002